What is Angelman Syndrome?

Angelman syndrome is a complex neuro-genetic disorder that primarily affects the nervous system.

Characteristic features of this condition include delayed development, intellectual disability, severe speech impairment, and problems with movement and balance. Most affected children also have recurrent seizures and a small head size. Delayed development becomes noticeable by the age of 6 to 12 months, and other common signs and symptoms usually appear in early childhood. Children with AS has hyperactivity, a short attention span, and a fascination with water are common. Most affected children also have difficulty sleeping and need less sleep than usual. They typically have a happy, excitable demeanor with frequent smiling, laughter, and hand-flapping movements. They require 24/7 care for their entire life, making independent life impossible.

Angelman syndrome is a disorder that occurs in roughly 1 in 15,000 to 20,000 live births.

Late or misdiagnosis may cause individuals to lose opportunities for early intervention programs, resources, personalized support and life-saving treatments.

To learn more, go to:


Angelman Syndrome Foundation



Foundation for Angelman Syndrome Therapeutics (FAST)